Fundamentals of Immunology: Death by Friendly Fire

  • Course StartSelf-paced
  • Course Duration7 weeks
  • Workload5-8 hours per week
  • Credit OfferedCertificate Available
  • TuitionSubscription

Learn about immune cells and how they attack pathogens, with emphasis on the mechanism of inducing apoptosis and details of Antibody Directed Cell-mediated Cytotoxicity.

Course Description

Course 3 of the three course Fundamentals of Immunology Specialization. Each course in the specialization presents material that builds on the previous course’s material.

Fundamentals of Immunology: Death by Friendly Fire introduces students to the basic functions of the adaptive and innate immune systems. The early lectures survey cells, tissues and organs using metaphors, cartoons and models to improve understanding and retention. After describing the form, function, origin and varieties of antibodies, subsequent lectures provide details on the mechanism of the generation of variation. The course provides animations of gene rearrangement and class switching and descriptions of affinity maturation correlated with detailed physical models of antibody structure. The final lecture reviews these concepts in anatomical context. Testing employs multiple choice questions testing facts, concepts, and application of principles. Questions may refer to diagrams, drawing and photographs used in lecture and reproduced in the outline.

What You’ll Learn:

A survey of immune cells and how they attack pathogens, with emphasis on the mechanism of inducing apoptosis and details of Antibody Directed Cell-mediated Cytotoxicity. The inflammatory response and mechanisms of generating tolerance, presented in sequence to emphasize the decision making involved in controlling attacks. A survey of autoimmune disease, their characteristics, cause and treatment. Survey of hypersensitivity reactions, including allergy, anaphylaxis, anemias, granulomas, and a variety of skin responses. This is accompanied by identification, prevention and treatment. The final discussion of preventing transplant rejection is preceded by a detailed unit on antibody technology and the methods of testing for incompatibility.

Course Trailer

Lecture Samples

 

Contact

Any questions? Please e-mail RiceOnline@rice.edu.

Professor Information

Picture of Dr. Alma Moon Novotny

Dr. Alma Moon Novotny

Alma Novotny earned her PhD from Purdue University in Developmental Biology under the direction of Michael Forman.  She has taught college courses for over forty years in plant and animal sciences, genetics and introductory, cell and developmental biology.  She has also written test question banks and contributed questions to both the MCAT and the GRE […]

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